| 2025 | | Brisbane | Round of 16 | Outdoor Hard | 63 63 | ResultadosCuadros |
| 2023 | | ATP Masters 1000 Cincinnati | Round of 16 | Outdoor Hard | 63 62 | ResultadosCuadros |
| 2022 | | ATP Masters 1000 Madrid | Round of 32 | Outdoor Clay | 63 62 | ResultadosCuadros |
| 2021 | | ATP Masters 1000 Paris | Round of 16 | Indoor Hard | W/O | ResultadosCuadros |
| 2020 | | Dubai | Semifinal | Outdoor Hard | 26 76(8) 61 | ResultadosCuadros |
| 2020 | | ATP Cup | Round Robin | Outdoor Hard | 63 62 | ResultadosCuadros |
| 2018 | | Australian Open | Round of 64 | Outdoor Hard | 46 63 61 63 | ResultadosCuadros |
| 2017 | | Eastbourne | Final | Outdoor Grass | 63 64 | ResultadosCuadros |
| 2016 | | US Open | Semifinal | Outdoor Hard | 63 62 36 62 | ResultadosCuadros |
| 2016 | | ATP Masters 1000 Canada | Semifinal | Outdoor Hard | 63 62 | ResultadosCuadros |
| 2014 | | ATP Masters 1000 Paris | Round of 16 | Indoor Hard | 63 76(2) | ResultadosCuadros |
| 2014 | | ATP Masters 1000 Canada | Round of 32 | Outdoor Hard | 62 67(4) 76(2) | ResultadosCuadros |
| 2013 | | ATP Masters 1000 Shanghai | Quarterfinal | Outdoor Hard | 67(4) 62 64 | ResultadosCuadros |
| 2011 | | ATP Masters 1000 Cincinnati | Quarterfinal | Outdoor Hard | 36 64 63 | ResultadosCuadros |
| 2011 | | ATP Masters 1000 Canada | Quarterfinal | Outdoor Hard | 62 61 | ResultadosCuadros |
| 2010 | | SRB vs. FRA DC Final | Round Robin | Indoor Hard | 62 62 64 | ResultadosCuadros |
| 2010 | | US Open | Quarterfinal | Outdoor Hard | 76(2) 61 62 | ResultadosCuadros |
| 2009 | | ATP Masters 1000 Paris | Final | Indoor Hard | 62 57 76(3) | ResultadosCuadros |
| 2008 | | Beijing Olympics | Quarterfinal | Outdoor Hard | 46 61 64 | ResultadosCuadros |
| 2006 | | Roland Garros | Round of 16 | Outdoor Clay | 76(5) 76(5) 63 | ResultadosCuadros |
| 2005 | | US Open | Round of 128 | Outdoor Hard | 75 46 76(5) 06 75 | ResultadosCuadros |
